PWE-148 Hepatotoxicity From Anabolic Androgenic Steroids Marketed as Dietary Supplements: Contribution from Atp8B1/Abcb11 Mutations?
نویسندگان
چکیده
منابع مشابه
Sports supplements and Anabolic Androgenic Steroids
Recently, the use of sport supplements has become so common among most athletes. These supplements may contain undeclared substances that are banned by such international authorities as WHO, IOC and WADA. The present study, thus, is aimed at examining the final sport supplement products in terms of banned substances and measuring the adulteration level in order to prove the safety of these prod...
متن کاملHepatotoxicity Associated with Anabolic Androgenic Steroids Present in Over-The- Counter Supplements: a Case Series
With the aim of improving their physical performance, athletes and non-athletes have been using anabolicandrogenic steroids (AAS). Over the past several decades, there has been an increase in the prevalence of AAS use without adequate supervision or monitoring. We present three cases of AAS-related liver injury with the intention to discuss the use of nutritional supplements as a growing public...
متن کاملAndrogenic Anabolic Steroids Use in Pakistan from the Perspective of Bodybuilders
Objectives: To determine the prevalence of androgenic anabolic steroids (AAS) use among bodybuilders in different cities of Pakistan. Methods: This cross-sectional study recruited 380 bodybuilders utilizing convenience sampling from different cities of Pakistan, including Karachi, Lahore, Multan, Quetta, Peshawar, Faisalabad, Rawalpindi, and Islamabad. The study was conducted over a period of ...
متن کاملAnabolic androgenic steroid-induced hepatotoxicity.
Anabolic androgenic steroids (AAS) have been abused for decades by both professional and amateur athletes in order to improve physical performance or muscle mass. AAS abuse can cause adverse effects, among which are hepatotoxic effects. These effects include cholestatic icterus and possibly peliosis hepatis and hepatocellular carcinoma or adenoma. In particular, 17α-alkylated AAS appear to be h...
متن کاملMetabolism of anabolic androgenic steroids.
Anabolic androgenic steroids (AAS) are misused to a high extent in sports by athletes to improve their physical performance. Sports federations consider the use of these drugs in sports as doping. The misuse of AAS is controlled by detection of the parent AAS (when excreted into urine) and (or) their metabolites in urine of athletes. I present a review of the metabolism of AAS. Testosterone is ...
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ژورنال
عنوان ژورنال: Gut
سال: 2013
ISSN: 0017-5749,1468-3288
DOI: 10.1136/gutjnl-2013-304907.436